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Lower-GWP direction
R454B offers a GWP of approximately 466 and zero ozone-depletion potential for approved new equipment.
Refrigenta›Refrigerants›R454B 22LB
Professional HVAC Supply
22LB CYLINDER
Next-generation refrigerant
R454B
Refrigerant
A 22LB professional-use cylinder for approved R454B air-conditioning, heat-pump and chiller equipment.
$99.94
$233.00
Save $133.06
In stock · Free U.S. shipping
- Lower-GWP R-410A alternative for equipment specifically designed and approved for R454B.
- A2L refrigerant blend with zero ozone-depletion potential.
- Factory-sealed, non-refillable 22LB disposable cylinder.
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Factory SealedProfessional-grade supply
Built for modern systems
Performance, safety and lower impact.
A clean editorial layout for Refrigenta—focused on the product, technical clarity and the needs of HVAC professionals.
2
Professional handling
Designed for qualified HVAC professionals following the equipment manual, SDS and all applicable A2L safety requirements.
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Matched performance
Capacity and efficiency characteristics suited to approved residential and light-commercial comfort systems.
Product profile
Technical details at a glance.
RefrigerantR454B
Zeotropic HFO/HFC blend
Net weight22LB / 10KG
Disposable supply cylinder
Safety classA2L
Mildly flammable—trained handling required
GWPApprox. 466
About 78% lower than R410A
ODPZero
Non-ozone-depleting formulation
Typical lubricantPOE
Confirm OEM requirements before service
CompositionR32 / R1234yf
69.9% / 31.1% nominal blend
UseApproved equipment
Not a universal drop-in replacement
Compatible applications
Where R454B is used.
Compatibility must always be verified against the equipment nameplate and the original manufacturer’s documentation.
Residential AC
Approved mini-split, multi-split, ducted and packaged comfort systems.
Light Commercial
Listed packaged and direct-expansion air-conditioning equipment.
Heat Pumps
Reversible heating and cooling units engineered specifically for R454B.
DX Chillers
Compatible chillers and cooling equipment approved by the OEM.
Professional workflow
A clearer service process.
VERIFY1
Confirm compatibility
Check the unit nameplate, manufacturer literature, refrigerant designation and required charge.
PREPARE2
Use A2L-rated tools
Follow the SDS, ventilate the work area and use approved recovery, charging and leak-detection equipment.
CHARGE3
Follow OEM procedure
Charge and commission strictly according to manufacturer instructions and applicable regulations.
⚠Important: R454B is an A2L refrigerant intended for qualified professionals. Do not mix refrigerants, do not use it as a universal drop-in replacement, and never charge equipment that is not approved for R454B.
Is R454B a direct drop-in replacement for R410A?
No. R454B is used in equipment specifically engineered and approved for it. Never add R454B to an R410A-only system unless the equipment manufacturer expressly permits a documented conversion procedure.
Can R454B be mixed with another refrigerant?
No. Mixing refrigerants can create unsafe operating conditions, compromise system performance and prevent proper recovery or recycling.
Is R454B flammable?
R454B is classified A2L, meaning it has lower toxicity and mild flammability. It requires trained handling, adequate ventilation and tools and procedures suitable for A2L refrigerants.
Which equipment can use this cylinder?
Only equipment whose nameplate and manufacturer documentation specify R454B. Common applications include approved air conditioners, heat pumps and DX chillers.
Is the 22LB cylinder refillable?
No. This listing is for a factory-sealed disposable cylinder. Handle, transport and dispose of it in accordance with applicable local and federal requirements.
Who should install or service R454B?
Service should be performed by a qualified HVAC professional who understands A2L refrigerants and follows all licensing, certification and safety requirements applicable to the work location.
Professional supply. Straightforward support.
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